CBD is primarily processed in the liver by a group of enzymes known as cytochrome P450 (CYP450). These enzymes are responsible for metabolizing a variety of compounds, including prescription medications, over-the-counter drugs, and even caffeine. Because CBD interacts with CYP450 enzymes, it may alter the way certain drugs are broken down in the body. This is why people taking medications that rely on liver metabolism—such as blood thinners, anti-seizure drugs, or cholesterol-lowering medications—should consult a healthcare professional before adding CBD to their routine.
As for the kidneys, their primary function is to filter waste and excess compounds from the bloodstream. While current research on CBD’s effect on kidney function is limited, studies so far indicate that CBD is generally well-tolerated in individuals with healthy kidney function. However, those with pre-existing kidney conditions or reduced kidney filtration capacity should discuss CBD use with their doctor to determine if any adjustments are necessary.
If you have a history of liver or kidney concerns, or if you take medications that rely on CYP450 metabolism, speaking with a qualified healthcare professional can help determine whether CBD is a good fit for your routine.
Check out the next frequently asked question: Can I take CBD with blood pressure medication?
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